MedPage Today: Brain structure disrupted in kids with autism

March 27, 2014

By John Gever, Deputy Managing Editor, MedPage Today
Reviewed by Zalman S. Agus, MD; Emeritus Professor, Perelman School of Medicine at the University of Pennsylvania and Dorothy Caputo, MA, BSN, RN, Nurse

Autopsied brains of autistic children showed "patches of disorganization" not seen in those from non-autistic children, a small study indicated.

Among 11 children diagnosed with autism who had died unexpectedly (most by drowning), 10 had "focal disruption of cortical laminar architecture," whereas 10 of 11 non-autistic children who also had died suddenly did not, according to Eric Courchesne, PhD, of the University of California San Diego, and colleagues.

Curtis Deutsch, PhD, of the University of Massachusetts Medical School in Worcester, Mass., is quoted.

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